Hepatitis c virus infection in type ii mixed cryoglobulinemia

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Hepatitis C Virus Infection and Mixed Cryoglobulinemia

Hepatitis C virus (HCV) chronic infection is recognized as the major cause of mixed cryoglobulinemia (MC). Its persistence represents a continuous stimulus for host immune system with production of circulating immune complexes (ICs), one-third of them with cryoprecipitate property. Several factors contribute to the biological activities of ICs, many of which are not completely known. Among them...

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[Anti-GOR antibodies in type II mixed cryoglobulinemia associated with hepatitis C virus infection].

The frequent association of chronic hepatitic C virus (HCV) infection and type II mixed cryoglobulinemia is considered to be one of the possible signs of interaction between the virus and the immune system. This could also be the case for the appearance of anti-GOR antibodies in serum, as they react with both viral and host antigens. We studied a group of patients with chronic hepatitis C infec...

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Molecular Signatures of Hepatitis C Virus (HCV)-Induced Type II Mixed Cryoglobulinemia (MCII)

The role of hepatitis C virus (HCV) infection in the induction of type II mixed cryoglobulinemia (MCII) and the possible establishment of related lymphoproliferative disorders, such as B-cell non-Hodgkin lymphoma (B-NHL), is well ascertained. However, the molecular pathways involved and the factors predisposing to the development of these HCV-related extrahepatic complications deserve further ...

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Infection of peripheral blood mononuclear cells by hepatitis C virus in mixed cryoglobulinemia.

A striking association between hepatitis C virus (HCV) infection and mixed cryoglobulinemia (MC) has been shown; thus, HCV seems to play an important etiopathogenetic role in this lymphoproliferative disorder. Because HCV is both a hepatotropic and lymphotropic virus, this study aimed to investigate the prevalence of HCV infection of peripheral blood mononuclear cells (PBMCs) in a series of 16 ...

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Low prevalence of hepatitis E virus in type II mixed cryoglobulinemia.

Sir, the relationship between hepatotropic viruses and mixed cryoglobulinemia (MC) has long been studied because of the frequent association of this lymphoproliferative disorder with chronic liver disease. 1 Initially, a link with hepatitis B virus (HBV) was proposed, but a recent survey of a large series of cryoglobulinemic patients did not support this theory. 2 Moreover, evidence of hepatiti...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 1993

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.1780361003